This handbook offers an in-depth analysis of political risk in the context of major geopolitical upheavals such as pandemics, nationalism, climate crisis, and technological advances. It brings together contributions from scholars and professionals worldwide to shed light on today’s complex challenges. The book explores the ethical, security, economic, and technological dimensions of risk. It addresses issues such as populism, protectionism, artificial intelligence, and militarized interdependence. Finally, it presents case studies and reflections on the management and future of political risk.